RERE-AS1

Across TCGA pan-cancer cohorts, RERE-AS1 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated RERE-AS1 data layer.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher RERE-AS1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated RERE-AS1 expression acts as an unfavorable survival marker, although some lineages such as SKCM and BRCA show a favorable association.

SKCM, BRCA, and KIRC are the cancer types where RERE-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SKCM	OS	Quartile	II,III,IV	0.633	0.232	<.001	58	view →
BRCA	OS	Tertile	All	0.590	0.465	<.001	50	view →
KIRC	DFS	Tertile	All	0.748	0.876	<.001	46	view →
HNSC	OS	Tertile	III,IV	0.455	0.209	.006	44	view →
DLBC	DFS	Median	II,III,IV	0.477	1.000	.005	41	view →
CESC	OS	Median	All	0.858	0.731	.004	20	view →
ACC	DFS	Median	All	0.302	0.707	.007	19	view →
UCS	OS	Median	II,III,IV	0.351	0.629	.033	10	view →
STAD	OS	Tertile	II,III,IV	0.749	0.445	.026	9	view →
LIHC	OS	Quartile	III,IV	0.253	0.685	.009	9	view →
CHOL	DFS	Median	All	0.673	0.135	.019	9	view →
PAAD	DFS	Tertile	II,III,IV	0.515	0.337	.022	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

RERE-AS1–SKCM (OS)

Open the SKCM breakdown →