REPS2

Across TCGA cell cohorts, REPS2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,785 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible REPS2-associated GO terms across cancer lineages are Negative regulation of innate immune response, Regulation of hypoxia-induced intrinsic apoptotic signaling pathway, and Negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway. Each is linked with REPS2 in more than 9 cancer types. Because this analysis shows association rather than direction, both REPS2-to-partner and partner-to-REPS2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of innate immune response grouped by REPS2-low versus REPS2-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (REPS2→partner) and Y-score (partner→REPS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Negative regulation of innate immune response →	+0.093	+1.082	.007	.006	3	10
OVARY	Regulation of hypoxia-induced intrinsic apoptotic signaling pathway →	+0.107	+0.934	.003	<.001	3	9
OVARY	Negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway →	+0.107	+0.934	.003	<.001	3	9
BLOOD_Lymphoma	Negative regulation of intrinsic apoptotic signaling pathway →	+0.063	+0.995	<.001	.002	3	9
BONE	Regulation of protein modification by small protein conjugation or removal →	+0.067	+0.532	<.001	.001	3	9
LUNG_NSCLC_LUAD	T cell mediated cytotoxicity →	+0.191	+1.157	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,785 associations by consensus.

Negative regulation of innate immune response by REPS2 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →