REPS1

Across TCGA patient cohorts, REPS1 mutation is significantly associated with the RNA expression of many other genes, with 4,333 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible REPS1-associated genes across cancer lineages are MTATP6P21, CCL5, and LINC00869. Each is linked with REPS1 in more than 2 cancer types. Because this analysis shows association rather than direction, both REPS1-to-partner and partner-to-REPS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MTATP6P21 grouped by REPS1-low versus REPS1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (REPS1→partner) and Y-score (partner→REPS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MTATP6P21 →	+0.203	+1.493	<.001	.009	3	3
UCEC	CCL5 →	+0.970	+1.721	<.001	.001	3	2
UCEC	LINC00869 →	-0.549	-2.471	<.001	<.001	3	2
CESC	OR5H2 →	+0.027	+4.559	.001	.006	3	2
CESC	RNU6-275P →	+0.270	+4.984	<.001	.003	3	2
CESC	IQCF6 →	+0.172	+3.653	.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,333 associations by consensus.

MTATP6P21 by REPS1 expression — UCEC

Explore this box plot interactively →