REPS1

Across TCGA cell cohorts, REPS1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,041 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible REPS1-associated GO terms across cancer lineages are Termination of RNA polymerase II transcription, DNA-templated DNA replication maintenance of fidelity, and Nuclear transport. Each is linked with REPS1 in more than 15 cancer types. Because this analysis shows association rather than direction, both REPS1-to-partner and partner-to-REPS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Termination of RNA polymerase II transcription grouped by REPS1-low versus REPS1-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (REPS1→partner) and Y-score (partner→REPS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Termination of RNA polymerase II transcription →	+0.138	+0.934	<.001	<.001	3	16
URINARY_TRACT	DNA-templated DNA replication maintenance of fidelity →	+0.091	+0.843	.002	.001	3	15
SOFT_TISSUE	Nuclear transport →	+0.069	+0.581	<.001	.003	3	15
SOFT_TISSUE	Nucleocytoplasmic transport →	+0.070	+0.581	<.001	.003	3	15
BLOOD_Lymphoma	Hair follicle placode formation →	+0.069	+0.711	.003	<.001	2	14
BONE	DNA integrity checkpoint signaling →	+0.096	+0.546	.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,041 associations by consensus.

Termination of RNA polymerase II transcription by REPS1 expression — SOFT_TISSUE

Explore this box plot interactively →