Across TCGA pan-cancer cohorts, REPIN1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated REPIN1 data layer compared with 25 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher REPIN1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated REPIN1 expression acts as an unfavorable survival marker, although some lineages such as UCEC and PDAC show a favorable association.

CCRCC, UCEC, and PDAC are the cancer types where REPIN1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Tertile	All	0.718	0.897	.009	14	view →
UCEC	DFS	Median	II,III,IV	0.872	0.543	.038	4	view →
PDAC	DFS	Median	All	0.438	0.242	.020	4	view →
HNSC	DFS	Median	IV	0.889	0.407	.042	2	view →
LUAD	DFS	Tertile	III,IV	0.995	0.625	.031	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: REPIN1 tumor-vs-normal RNA expression · all REPIN1 data types