Across TCGA patient cohorts, REPIN1 mutation is significantly associated with the total protein of many other genes, with 8 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible REPIN1-associated genes across cancer lineages are EGFR_pY1068, STAT3_pY705, and Tuberin. Each is linked with REPIN1 in more than 1 cancer types. Because this analysis shows association rather than direction, both REPIN1-to-partner and partner-to-REPIN1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (REPIN1→partner) and Y-score (partner→REPIN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EGFR_pY1068 →	-0.320	-2.321	.011	.035	3	2
UCEC	STAT3_pY705 →	-0.385	-3.159	.003	.019	3	1
UCEC	Tuberin →	+0.391	+2.321	.003	.035	3	1
UCEC	Caspase-7-cleavedD198 →	+0.643	+2.827	.031	.035	3	1
UCEC	4E-BP1 →	+0.480	+3.459	<.001	.005	1	2
UCEC	p62 Lck ligand →	+0.670	+3.459	<.001	.005	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

Exploration

REPIN1 survival (RNA) · tumor vs normal (RNA) · all REPIN1 data types