Across TCGA cell cohorts, REPIN1 mutation is significantly associated with the RNA expression of many other genes, with 595 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible REPIN1-associated genes across cancer lineages are PPEF2, PFN3, and CLCN3. Each is linked with REPIN1 in more than 2 cancer types. Because this analysis shows association rather than direction, both REPIN1-to-partner and partner-to-REPIN1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (REPIN1→partner) and Y-score (partner→REPIN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	PPEF2 →	+0.025	+2.736	.003	.002	3	3
LARGE_INTESTINE	PFN3 →	+0.064	+2.397	<.001	.003	3	2
LARGE_INTESTINE	CLCN3 →	+0.633	+3.502	.005	.001	3	2
LARGE_INTESTINE	TCEANC2 →	+0.360	+3.588	.005	<.001	3	2
LARGE_INTESTINE	SLC25A35 →	+0.746	+3.067	.002	.009	3	2
LARGE_INTESTINE	ZFAND4 →	+0.823	+3.502	.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 595 associations by consensus.

Exploration

REPIN1 survival (RNA) · tumor vs normal (RNA) · all REPIN1 data types