REP15

Across TCGA cell cohorts, REP15 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,221 significant associations in total. BONE shows the largest number of these associations.

The most reproducible REP15-associated GO terms across cancer lineages are Cortical microtubule organization, Negative regulation of T-helper 17 type immune response, and Schwann cell development. Each is linked with REP15 in more than 7 cancer types. Because this analysis shows association rather than direction, both REP15-to-partner and partner-to-REP15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cortical microtubule organization grouped by REP15-low versus REP15-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (REP15→partner) and Y-score (partner→REP15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Cortical microtubule organization →	+0.129	+0.598	.001	.001	3	8
BONE	Negative regulation of T-helper 17 type immune response →	+0.117	+0.907	.007	.009	3	6
KIDNEY	Schwann cell development →	+0.075	+0.314	.003	.008	3	6
BLOOD_Leukemia	Cytoplasmic microtubule organization →	+0.046	+0.277	<.001	.002	2	7
BONE	Sulfur amino acid biosynthetic process →	-0.143	-0.503	.001	.003	3	6
BONE	Positive regulation of plasma membrane repair →	+0.338	+0.766	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,221 associations by consensus.

Cortical microtubule organization by REP15 expression — SOFT_TISSUE

Explore this box plot interactively →