RENBP

Across TCGA pan-cancer cohorts, RENBP mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated RENBP data layer compared with 29 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher RENBP mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated RENBP expression acts as an unfavorable survival marker, although some lineages such as CCRCC and PDAC show a favorable association.

CCRCC, COAD, and GBM are the cancer types where RENBP mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Tertile	III,IV	0.935	0.553	.007	28	view →
COAD	DFS	Median	All	0.888	1.000	.023	18	view →
GBM	OS	Tertile	All	0.384	0.701	.002	16	view →
PDAC	DFS	Median	IV	0.934	0.250	.024	3	view →
HNSC	DFS	Median	II,III,IV	0.916	0.976	.048	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

RENBP–CCRCC (OS)

Open the CCRCC breakdown →