RENBP

Across TCGA cell cohorts, RENBP mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RENBP-associated genes across cancer lineages are ADRA1A, SRY, and SIRPD. Each is linked with RENBP in more than 1 cancer types. Because this analysis shows association rather than direction, both RENBP-to-partner and partner-to-RENBP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ADRA1A grouped by RENBP-low versus RENBP-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RENBP→partner) and Y-score (partner→RENBP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	ADRA1A →	+0.227	+4.705	<.001	.003	3	1
BLOOD_Leukemia	SRY →	+0.034	+4.874	<.001	.002	3	1
LARGE_INTESTINE	SIRPD →	+0.021	+4.977	<.001	.007	3	1
LARGE_INTESTINE	OR13G1 →	+0.032	+5.415	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

ADRA1A by RENBP expression — BLOOD_Leukemia

Explore this box plot interactively →