REN

Across TCGA patient cohorts, REN RNA expression is significantly associated with the go_rna of many other GO terms, with 7,110 significant associations in total. TGCT shows the largest number of these associations.

The most reproducible REN-associated GO terms across cancer lineages are Drinking behavior, Response to cGMP, and Regulation of blood volume by renin-angiotensin. Each is linked with REN in more than 13 cancer types. Because this analysis shows association rather than direction, both REN-to-partner and partner-to-REN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Drinking behavior grouped by REN-low versus REN-high in KIRC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (REN→partner) and Y-score (partner→REN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIRC	Drinking behavior →	+0.199	+3.401	<.001	<.001	3	14
ACC	Response to cGMP →	+0.093	+2.764	<.001	<.001	3	13
KIRC	Regulation of blood volume by renin-angiotensin →	+0.124	+3.418	<.001	<.001	3	12
ACC	Short-chain fatty acid catabolic process →	+0.069	+2.284	<.001	<.001	3	12
TGCT	Cell surface receptor signaling pathway involved in heart development →	+0.095	+1.500	<.001	<.001	3	11
STAD	Lung epithelium development →	+0.063	+0.196	<.001	.008	1	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,110 associations by consensus.

Drinking behavior by REN expression — KIRC

Explore this box plot interactively →