REN

Across TCGA patient cohorts, REN protein abundance is significantly associated with the RNA expression of many other genes, with 1,143 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible REN-associated genes across cancer lineages are SLC52A3, MYCL, and SH3BGRL3. Each is linked with REN in more than 1 cancer types. Because this analysis shows association rather than direction, both REN-to-partner and partner-to-REN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, REN versus SLC52A3 in UCEC, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (REN→partner) and Y-score (partner→REN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SLC52A3 →	+1.188	+0.887	.007	.002	3	1
UCEC	MYCL →	+0.830	+0.914	.002	.002	3	1
UCEC	SH3BGRL3 →	-0.453	-1.024	.003	.008	3	1
UCEC	PPP1R18 →	-0.602	-1.076	.003	.009	3	1
UCEC	NPFFR1 →	+0.631	+1.006	.001	<.001	3	1
UCEC	DDX4 →	+0.400	+0.997	.007	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,143 associations by consensus.

REN vs SLC52A3 — UCEC

Explore this scatter interactively →