REM1

Across TCGA cell cohorts, REM1 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible REM1-associated genes across cancer lineages are S100G, ASB17, and BPIFA1. Each is linked with REM1 in more than 1 cancer types. Because this analysis shows association rather than direction, both REM1-to-partner and partner-to-REM1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, S100G grouped by REM1-low versus REM1-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (REM1→partner) and Y-score (partner→REM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	S100G →	+0.179	+5.321	<.001	.005	3	1
OVARY	ASB17 →	+0.023	+5.807	<.001	.001	3	1
LARGE_INTESTINE	BPIFA1 →	+0.186	+4.273	<.001	.006	3	1
LUNG_NSCLC_LUAD	GNG8 →	+0.271	+4.887	.001	.009	3	1
LUNG_NSCLC_LUAD	MT1HL1 →	+0.173	+6.266	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

S100G by REM1 expression — CNS

Explore this box plot interactively →