RELT

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RELT protein abundance is significantly associated with the RNA expression of many other genes, with 973 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RELT-associated genes across cancer lineages are EHHADH, SOX3, and RPL12P42. Each is linked with RELT in more than 1 cancer types. Because this analysis shows association rather than direction, both RELT-to-partner and partner-to-RELT results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RELT versus EHHADH in GBM, with a Pearson correlation of 0.80.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RELT→partner) and Y-score (partner→RELT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMEHHADH →+0.700+0.456<.001.00231
GBMSOX3 →+1.500+0.456.001.00231
GBMRPL12P42 →-0.806-0.363<.001.00831
GBMHNRNPA1P37 →-0.693-0.429.004.00331
GBMRNU2-51P →-1.638-0.413.004.00731
GBMLINC02051 →+2.270+0.456<.001.00231
Each partner links to its Q-omics profile. Showing the 6 strongest of 973 associations by consensus.

RELT vs EHHADH — GBM

Per-sample scatter of RELT vs EHHADH in GBM (Pearson r = 0.80).

Explore this scatter interactively →

Exploration