Across TCGA patient cohorts, RELN RNA expression is significantly associated with the protein abundance of many other proteins, with 18,786 significant associations in total. GBM shows the largest number of these associations.

The most reproducible RELN-associated proteins across cancer lineages are PRKACB, CCL21, and CDH13. Each is linked with RELN in more than 4 cancer types. Because this analysis shows association rather than direction, both RELN-to-partner and partner-to-RELN results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RELN→partner) and Y-score (partner→RELN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	PRKACB →	+0.396	+0.940	<.001	<.001	3	5
HNSC	CCL21 →	+0.750	+0.640	<.001	<.001	3	5
UCEC	CDH13 →	+0.840	+1.323	<.001	.001	3	5
BRCA	DCLK1 →	+0.642	+0.593	<.001	.003	3	5
LSCC	DPYSL2 →	+0.452	+1.025	<.001	<.001	3	5
BRCA	AKAP12_S1331 →	+0.686	+0.599	.004	.003	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,786 associations by consensus.

Exploration

RELN survival (RNA) · tumor vs normal (RNA) · all RELN data types