Across TCGA cell cohorts, RELN RNA expression is significantly associated with the RNA expression of many other genes, with 3,610 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RELN-associated genes across cancer lineages are AMOTL1, CCSER1, and PRKAR2B. Each is linked with RELN in more than 2 cancer types. Because this analysis shows association rather than direction, both RELN-to-partner and partner-to-RELN results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RELN→partner) and Y-score (partner→RELN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	AMOTL1 →	+1.767	+2.077	.001	.004	3	3
BLOOD_Myeloma	CCSER1 →	+2.065	+4.552	<.001	<.001	3	3
BLOOD_Leukemia	PRKAR2B →	+1.823	+1.489	<.001	<.001	3	3
BLOOD_Leukemia	CLCN4 →	+1.365	+1.267	<.001	.001	3	3
BONE	FST →	+3.340	+1.077	<.001	.008	3	3
BLOOD_Leukemia	ELAPOR2 →	+1.461	+0.786	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,610 associations by consensus.

Exploration

RELN survival (RNA) · tumor vs normal (RNA) · all RELN data types