Across TCGA cell cohorts, RELN RNA expression is significantly associated with the go_rna of many other GO terms, with 1,615 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible RELN-associated GO terms across cancer lineages are Spinal cord motor neuron migration, Lateral motor column neuron migration, and NMDA glutamate receptor clustering. Each is linked with RELN in more than 7 cancer types. Because this analysis shows association rather than direction, both RELN-to-partner and partner-to-RELN results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RELN→partner) and Y-score (partner→RELN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Spinal cord motor neuron migration →	+1.425	+3.159	<.001	<.001	3	8
BLOOD_Myeloma	Lateral motor column neuron migration →	+1.425	+3.159	<.001	<.001	3	8
BLOOD_Myeloma	NMDA glutamate receptor clustering →	+1.577	+4.642	<.001	<.001	3	6
KIDNEY	Regulation of synaptic activity →	+1.468	+3.641	<.001	<.001	3	6
KIDNEY	Transcription elongation-coupled chromatin remodeling →	+0.068	+2.399	.003	.006	3	5
SOFT_TISSUE	Synaptic transmission, glutamatergic →	-0.067	-1.517	.001	.007	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,615 associations by consensus.

Exploration

RELN survival (RNA) · tumor vs normal (RNA) · all RELN data types