RELL1

Across TCGA cell cohorts, RELL1 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RELL1-associated genes across cancer lineages are S100G, RESP18, and ITGAD. Each is linked with RELL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both RELL1-to-partner and partner-to-RELL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, S100G grouped by RELL1-low versus RELL1-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RELL1→partner) and Y-score (partner→RELL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	S100G →	+0.054	+4.867	.001	.009	3	1
BLOOD_Lymphoma	RESP18 →	+0.031	+5.209	<.001	.005	3	1
LARGE_INTESTINE	ITGAD →	+0.015	+4.095	<.001	.009	3	1
LARGE_INTESTINE	SCGB3A2 →	+0.384	+4.095	<.001	.009	3	1
LARGE_INTESTINE	BPIFA1 →	+0.287	+4.273	<.001	.006	3	1
LARGE_INTESTINE	PRAMEF20 →	+0.015	+5.022	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

S100G by RELL1 expression — BLOOD_Lymphoma

Explore this box plot interactively →