RELCH

Across TCGA pan-cancer cohorts, RELCH Mutation is linked to patient survival in 5 of 34 cancer types, making it a survival-associated RELCH data layer compared with 20 for mass-spec protein and 4 for mass-spec protein.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher RELCH Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated RELCH expression acts as an unfavorable survival marker.

KIRP, COAD, and SCLC are the cancer types where RELCH Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	OS	Median	All	0.132	0.904	<.001	36	view →
COAD	DFS	Median	All	0.323	0.705	<.001	14	view →
SCLC	OS	Median	II,III,IV	0.192	0.645	.014	9	view →
SARC	DFS	Median	All	0.063	0.613	<.001	6	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

RELCH–KIRP (OS)

Open the KIRP breakdown →