RELCH

Across TCGA patient cohorts, RELCH protein abundance is significantly associated with the RNA expression of many other genes, with 12,552 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RELCH-associated genes across cancer lineages are VPS4B, NARS1, and ATP5F1A. Each is linked with RELCH in more than 7 cancer types. Because this analysis shows association rather than direction, both RELCH-to-partner and partner-to-RELCH results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RELCH versus VPS4B in HNSC, with a Pearson correlation of 0.31.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RELCH→partner) and Y-score (partner→RELCH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	VPS4B →	+0.773	+0.435	<.001	<.001	3	8
COAD	NARS1 →	+0.531	+0.192	<.001	<.001	3	7
COAD	ATP5F1A →	+0.622	+0.199	<.001	<.001	3	7
OV	ATP8B1 →	+0.754	+0.412	.003	<.001	3	7
COAD	TXNL4A →	+0.580	+0.297	<.001	<.001	3	6
GBM	GBGT1 →	-0.514	-0.168	.001	.005	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,552 associations by consensus.

RELCH vs VPS4B — HNSC

Explore this scatter interactively →