RELCH

Across TCGA cell cohorts, RELCH RNA expression is significantly associated with the go_rna of many other GO terms, with 3,846 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible RELCH-associated GO terms across cancer lineages are Negative regulation of exosomal secretion, Centriole-centriole cohesion, and Ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway. Each is linked with RELCH in more than 12 cancer types. Because this analysis shows association rather than direction, both RELCH-to-partner and partner-to-RELCH results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of exosomal secretion grouped by RELCH-low versus RELCH-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RELCH→partner) and Y-score (partner→RELCH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Negative regulation of exosomal secretion →	+0.180	+1.065	<.001	<.001	3	13
OVARY	Centriole-centriole cohesion →	+0.079	+0.672	<.001	.001	3	13
LUNG_SCLC	Ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway →	+0.151	+0.825	<.001	<.001	3	12
LARGE_INTESTINE	Left ventricular cardiac muscle tissue morphogenesis →	+0.578	+0.831	<.001	<.001	3	12
SOFT_TISSUE	Vesicle-mediated transport between endosomal compartments →	+0.061	+0.797	.001	<.001	2	13
LARGE_INTESTINE	Non-lytic viral release →	+0.133	+0.994	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,846 associations by consensus.

Negative regulation of exosomal secretion by RELCH expression — BREAST

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