REL

Across TCGA patient cohorts, REL mutation is significantly associated with the RNA expression of many other genes, with 2,243 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible REL-associated genes across cancer lineages are CCDC137P, RNA5SP420, and LINC01151. Each is linked with REL in more than 1 cancer types. Because this analysis shows association rather than direction, both REL-to-partner and partner-to-REL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCDC137P grouped by REL-low versus REL-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (REL→partner) and Y-score (partner→REL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CCDC137P →	+0.066	+1.528	.008	.006	3	2
UCEC	RNA5SP420 →	+0.510	+1.889	<.001	.002	3	2
UCEC	LINC01151 →	+0.340	+1.618	.008	.004	3	2
CESC	MIR3908 →	+0.214	+3.760	<.001	.004	3	2
LUAD	MIR588 →	+0.405	+5.631	<.001	.004	3	2
LUAD	E2F6P1 →	+0.054	+5.099	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,243 associations by consensus.

CCDC137P by REL expression — UCEC

Explore this box plot interactively →