Across TCGA patient cohorts, REG1CP mutation is significantly associated with the total protein of many other genes, with 15 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible REG1CP-associated genes across cancer lineages are JNK2, p53, and HSP70. Each is linked with REG1CP in more than 1 cancer types. Because this analysis shows association rather than direction, both REG1CP-to-partner and partner-to-REG1CP results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (REG1CP→partner) and Y-score (partner→REG1CP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	JNK2 →	+0.268	+3.000	.019	.037	3	2
SKCM	p53 →	+0.241	+3.017	.025	.019	3	2
LUSC	HSP70 →	+0.434	+1.816	.015	.015	3	1
LUSC	Paxillin →	-0.330	-3.459	.026	.005	3	1
LUSC	PKC-a →	-0.187	-2.294	.016	.006	3	1
LUSC	4E-BP1_pT70 →	+0.269	+2.331	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

Exploration

REG1CP survival (RNA) · tumor vs normal (RNA) · all REG1CP data types