REEP6

Across TCGA patient cohorts, REEP6 mutation is significantly associated with the RNA expression of many other genes, with 66 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible REEP6-associated genes across cancer lineages are RNU6-1242P, OR5BM1P, and LINC01848. Each is linked with REEP6 in more than 1 cancer types. Because this analysis shows association rather than direction, both REEP6-to-partner and partner-to-REEP6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1242P grouped by REEP6-low versus REEP6-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (REEP6→partner) and Y-score (partner→REEP6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-1242P →	+0.481	+3.344	.001	.008	3	2
UCEC	OR5BM1P →	+0.073	+5.414	<.001	.001	3	2
UCEC	LINC01848 →	+0.158	+3.302	<.001	.009	3	2
COAD	MIR1915 →	+0.492	+4.893	<.001	.005	3	2
SKCM	RNA5SP497 →	+0.444	+5.159	<.001	.007	3	1
SKCM	LINC02825 →	+0.235	+5.097	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 66 associations by consensus.

RNU6-1242P by REEP6 expression — UCEC

Explore this box plot interactively →