REEP6

Across TCGA cell cohorts, REEP6 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,480 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible REEP6-associated GO terms across cancer lineages are Fatty acid beta-oxidation, Fatty acid beta-oxidation using acyl-CoA dehydrogenase, and Monocarboxylic acid catabolic process. Each is linked with REEP6 in more than 11 cancer types. Because this analysis shows association rather than direction, both REEP6-to-partner and partner-to-REEP6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Fatty acid beta-oxidation grouped by REEP6-low versus REEP6-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (REEP6→partner) and Y-score (partner→REEP6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Fatty acid beta-oxidation →	+0.113	+2.307	<.001	<.001	3	12
LIVER	Fatty acid beta-oxidation using acyl-CoA dehydrogenase →	+0.107	+2.262	.002	.001	3	11
OESOPHAGUS	Monocarboxylic acid catabolic process →	+0.086	+1.176	<.001	<.001	3	11
OESOPHAGUS	Fatty acid catabolic process →	+0.090	+1.656	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Energy coupled proton transmembrane transport, against electrochemical gradient →	+0.099	+1.132	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Electron transport coupled proton transport →	+0.099	+1.132	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,480 associations by consensus.

Fatty acid beta-oxidation by REEP6 expression — LIVER

Explore this box plot interactively →