REEP5

Across TCGA cell cohorts, REEP5 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,344 significant associations in total. BONE shows the largest number of these associations.

The most reproducible REEP5-associated GO terms across cancer lineages are Regulation of protein processing, Positive regulation of protein exit from endoplasmic reticulum, and Regulation of double-strand break repair via homologous recombination. Each is linked with REEP5 in more than 9 cancer types. Because this analysis shows association rather than direction, both REEP5-to-partner and partner-to-REEP5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of protein processing grouped by REEP5-low versus REEP5-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (REEP5→partner) and Y-score (partner→REEP5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of protein processing →	+0.144	+1.100	<.001	<.001	3	10
BONE	Positive regulation of protein exit from endoplasmic reticulum →	+0.131	+1.138	<.001	<.001	3	10
BONE	Regulation of double-strand break repair via homologous recombination →	-0.083	-1.027	<.001	<.001	3	10
BONE	Insulin processing →	+0.153	+0.958	<.001	.006	3	10
BONE	'de novo' IMP biosynthetic process →	-0.153	-0.944	.001	.002	3	10
SOFT_TISSUE	Negative regulation of immune response →	+0.076	+0.711	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,344 associations by consensus.

Regulation of protein processing by REEP5 expression — BONE

Explore this box plot interactively →