REELD1

Across TCGA cell cohorts, REELD1 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,639 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible REELD1-associated GO terms across cancer lineages are Macroautophagy, Regulation of protein localization to mitochondrion, and Negative regulation of canonical NF-kappaB signal transduction. Each is linked with REELD1 in more than 7 cancer types. Because this analysis shows association rather than direction, both REELD1-to-partner and partner-to-REELD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Macroautophagy grouped by REELD1-low versus REELD1-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (REELD1→partner) and Y-score (partner→REELD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Macroautophagy →	+0.027	+0.566	.002	.008	3	8
LARGE_INTESTINE	Regulation of protein localization to mitochondrion →	+0.110	+0.085	<.001	.007	3	8
LUNG_NSCLC_LUAD	Negative regulation of canonical NF-kappaB signal transduction →	+0.046	+0.190	<.001	.002	3	7
OVARY	L-kynurenine catabolic process →	-0.687	-0.161	.003	.003	3	6
BLOOD_Leukemia	Adenylate cyclase-modulating G protein-coupled receptor signaling pathway →	-0.028	-0.156	<.001	<.001	3	6
UPPER_AERODIGESTIVE_TRACT	Autophagosome organization →	+0.037	+0.082	.005	.006	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,639 associations by consensus.

Macroautophagy by REELD1 expression — BLOOD_Lymphoma

Explore this box plot interactively →