RECQL5

Across TCGA patient cohorts, RECQL5 protein abundance is significantly associated with the RNA expression of many other genes, with 11,081 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RECQL5-associated genes across cancer lineages are SNHG16, NAT9, and CREB3L1. Each is linked with RECQL5 in more than 5 cancer types. Because this analysis shows association rather than direction, both RECQL5-to-partner and partner-to-RECQL5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RECQL5 versus SNHG16 in OV, with a Pearson correlation of 0.32.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RECQL5→partner) and Y-score (partner→RECQL5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SNHG16 →	+0.734	+0.243	<.001	.008	3	6
BRCA	NAT9 →	+0.835	+0.365	<.001	<.001	3	5
BRCA	CREB3L1 →	-1.564	-0.315	<.001	.004	3	5
LSCC	BRCA1 →	+0.801	+0.288	<.001	<.001	3	5
LSCC	NUP85 →	+0.457	+0.286	<.001	<.001	3	5
BRCA	MRM1 →	+0.712	+0.280	<.001	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,081 associations by consensus.

RECQL5 vs SNHG16 — OV

Explore this scatter interactively →