RDX

Across TCGA patient cohorts, RDX protein abundance is significantly associated with the RNA expression of many other genes, with 11,535 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RDX-associated genes across cancer lineages are FDX1, REXO2, and ETV5-AS1. Each is linked with RDX in more than 6 cancer types. Because this analysis shows association rather than direction, both RDX-to-partner and partner-to-RDX results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RDX versus FDX1 in OV, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RDX→partner) and Y-score (partner→RDX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	FDX1 →	+0.558	+0.240	.001	.003	3	7
LSCC	REXO2 →	+0.526	+0.236	<.001	.001	3	5
UCEC	ETV5-AS1 →	-0.918	-0.168	<.001	<.001	3	4
GBM	CNN3 →	+0.529	+0.290	<.001	.009	3	4
LUAD	DLAT →	+0.448	+0.253	<.001	.001	3	4
CCRCC	PDE2A →	+0.833	+0.177	.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,535 associations by consensus.

RDX vs FDX1 — OV

Explore this scatter interactively →