RDX

Across TCGA cell cohorts, RDX RNA expression is significantly associated with the go_rna of many other GO terms, with 5,089 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RDX-associated GO terms across cancer lineages are Negative regulation of receptor catabolic process, Regulation of Rap protein signal transduction, and Meiotic sister chromatid cohesion, centromeric. Each is linked with RDX in more than 11 cancer types. Because this analysis shows association rather than direction, both RDX-to-partner and partner-to-RDX results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of receptor catabolic process grouped by RDX-low versus RDX-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RDX→partner) and Y-score (partner→RDX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Negative regulation of receptor catabolic process →	+0.178	+1.125	<.001	<.001	3	12
LARGE_INTESTINE	Regulation of Rap protein signal transduction →	+0.974	+3.369	<.001	<.001	3	12
BREAST	Meiotic sister chromatid cohesion, centromeric →	+0.174	+1.294	<.001	.003	3	12
LARGE_INTESTINE	Regulation of postsynaptic neurotransmitter receptor diffusion trapping →	+1.444	+3.631	<.001	<.001	3	11
OVARY	Ether catabolic process →	+0.240	+1.319	<.001	.001	3	11
LUNG_NSCLC_LUAD	Positive regulation of TORC2 signaling →	+0.119	+1.419	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,089 associations by consensus.

Negative regulation of receptor catabolic process by RDX expression — BLOOD_Leukemia

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