RDM1P1

Across TCGA patient cohorts, RDM1P1 RNA expression is significantly associated with the go_rna of many other GO terms, with 377 significant associations in total. LAML shows the largest number of these associations.

The most reproducible RDM1P1-associated GO terms across cancer lineages are Positive regulation of receptor signaling pathway via STAT, Retrograde trans-synaptic signaling, and Regulation of skeletal muscle satellite cell proliferation. Each is linked with RDM1P1 in more than 1 cancer types. Because this analysis shows association rather than direction, both RDM1P1-to-partner and partner-to-RDM1P1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of receptor signaling pathway via STAT grouped by RDM1P1-low versus RDM1P1-high in LAML.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RDM1P1→partner) and Y-score (partner→RDM1P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LAML	Positive regulation of receptor signaling pathway via STAT →	+0.041	+0.084	.004	.001	3	2
ESCA	Retrograde trans-synaptic signaling →	+0.059	+0.024	.001	.001	3	1
LAML	Regulation of skeletal muscle satellite cell proliferation →	+0.079	+0.085	<.001	.001	3	1
LAML	Negative regulation of meiotic cell cycle phase transition →	-0.060	-0.086	.003	.001	3	1
LAML	Regulation of TRAIL-activated apoptotic signaling pathway →	+0.085	+0.130	.001	<.001	3	1
LAML	Mucopolysaccharide metabolic process →	-0.022	-0.086	.003	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 377 associations by consensus.

Positive regulation of receptor signaling pathway via STAT by RDM1P1 expression — LAML

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