RDH8

Across TCGA patient cohorts, RDH8 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,346 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible RDH8-associated GO terms across cancer lineages are UDP-N-acetylglucosamine biosynthetic process, Pyrimidine-containing compound salvage, and Extracellular matrix disassembly. Each is linked with RDH8 in more than 12 cancer types. Because this analysis shows association rather than direction, both RDH8-to-partner and partner-to-RDH8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, UDP-N-acetylglucosamine biosynthetic process grouped by RDH8-low versus RDH8-high in THYM.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RDH8→partner) and Y-score (partner→RDH8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
THYM	UDP-N-acetylglucosamine biosynthetic process →	+0.051	+0.023	<.001	.002	3	13
MESO	Pyrimidine-containing compound salvage →	+0.056	+0.068	.001	.001	1	13
DLBC	Extracellular matrix disassembly →	+0.054	+0.166	<.001	.002	2	12
THYM	Neuroinflammatory response →	+0.046	+0.024	<.001	<.001	3	11
THYM	Bone development →	+0.035	+0.021	<.001	<.001	3	10
STAD	Regulation of response to cytokine stimulus →	+0.036	+0.328	<.001	.005	2	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,346 associations by consensus.

UDP-N-acetylglucosamine biosynthetic process by RDH8 expression — THYM

Explore this box plot interactively →