RDH5

Across TCGA patient cohorts, RDH5 protein abundance is significantly associated with the RNA expression of many other genes, with 2,597 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible RDH5-associated genes across cancer lineages are CLIC5, CYB5R1, and CPA3. Each is linked with RDH5 in more than 1 cancer types. Because this analysis shows association rather than direction, both RDH5-to-partner and partner-to-RDH5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RDH5 versus CLIC5 in OV, with a Pearson correlation of 0.70.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RDH5→partner) and Y-score (partner→RDH5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CLIC5 →	+2.165	+0.748	.004	.006	3	2
BRCA	CYB5R1 →	+1.368	+2.035	.002	<.001	3	2
BRCA	CPA3 →	+3.195	+1.159	<.001	.004	3	2
OV	SLC25A33 →	-0.827	-0.771	.003	.004	3	2
OV	SNX2 →	+1.114	+0.937	.001	.002	3	2
OV	LINC01697 →	+1.661	+0.748	.002	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,597 associations by consensus.

RDH5 vs CLIC5 — OV

Explore this scatter interactively →