RDH16

Across TCGA patient cohorts, RDH16 protein abundance is significantly associated with the RNA expression of many other genes, with 1,087 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RDH16-associated genes across cancer lineages are RGS4, PDZRN3, and PLP1. Each is linked with RDH16 in more than 1 cancer types. Because this analysis shows association rather than direction, both RDH16-to-partner and partner-to-RDH16 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RDH16 versus RGS4 in HNSC, with a Pearson correlation of 0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RDH16→partner) and Y-score (partner→RDH16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RGS4 →	+1.228	+1.175	.004	.001	3	1
HNSC	PDZRN3 →	+1.052	+1.286	.004	.002	3	1
HNSC	PLP1 →	+0.533	+1.028	.006	.008	3	1
HNSC	STARD13 →	+0.615	+1.186	.002	.006	3	1
HNSC	UBAC2 →	+0.476	+1.121	.008	.007	3	1
HNSC	MBNL2 →	+0.587	+1.426	.003	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,087 associations by consensus.

RDH16 vs RGS4 — HNSC

Explore this scatter interactively →