RDH16

Across TCGA cell cohorts, RDH16 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,800 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RDH16-associated GO terms across cancer lineages are Taurine biosynthetic process, Alkanesulfonate biosynthetic process, and Negative regulation of myoblast fusion. Each is linked with RDH16 in more than 9 cancer types. Because this analysis shows association rather than direction, both RDH16-to-partner and partner-to-RDH16 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Taurine biosynthetic process grouped by RDH16-low versus RDH16-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RDH16→partner) and Y-score (partner→RDH16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Taurine biosynthetic process →	+0.729	+0.172	<.001	<.001	3	10
OVARY	Alkanesulfonate biosynthetic process →	+0.729	+0.172	<.001	<.001	3	10
OVARY	Negative regulation of myoblast fusion →	+0.114	+0.195	<.001	.001	3	10
OVARY	Regulation of myoblast fusion →	+0.102	+0.205	<.001	<.001	3	9
OVARY	Negative regulation of syncytium formation by plasma membrane fusion →	+0.109	+0.195	<.001	.001	3	9
PANCREAS	Dorsal aorta morphogenesis →	-0.520	-0.250	.006	.006	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,800 associations by consensus.

Taurine biosynthetic process by RDH16 expression — OVARY

Explore this box plot interactively →