RDH14

Across TCGA patient cohorts, RDH14 protein abundance is significantly associated with the RNA expression of many other genes, with 9,591 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible RDH14-associated genes across cancer lineages are TPM4, ADAMTS5, and PBK. Each is linked with RDH14 in more than 3 cancer types. Because this analysis shows association rather than direction, both RDH14-to-partner and partner-to-RDH14 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RDH14 versus TPM4 in BRCA, with a Pearson correlation of -0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RDH14→partner) and Y-score (partner→RDH14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	TPM4 →	-0.640	-0.260	<.001	<.001	3	4
OV	ADAMTS5 →	-0.848	-0.201	.003	.002	3	4
COAD	PBK →	-1.259	-0.193	<.001	.001	3	4
LUAD	CKAP2L →	-0.768	-0.226	.001	<.001	3	4
COAD	ESCO2 →	-0.875	-0.160	<.001	.002	3	4
LUAD	MCM10 →	-0.911	-0.236	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,591 associations by consensus.

RDH14 vs TPM4 — BRCA

Explore this scatter interactively →