RDH13

Across TCGA patient cohorts, RDH13 mutation is significantly associated with the total protein of many other genes, with 14 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RDH13-associated genes across cancer lineages are S6, SF2, and FASN. Each is linked with RDH13 in more than 1 cancer types. Because this analysis shows association rather than direction, both RDH13-to-partner and partner-to-RDH13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, S6 grouped by RDH13-low versus RDH13-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RDH13→partner) and Y-score (partner→RDH13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	S6 →	+0.474	+2.849	.035	.034	3	1
STAD	SF2 →	+0.440	+2.828	.022	.035	3	1
UCEC	FASN →	+0.558	+2.321	.004	.035	3	1
UCEC	ACC_pS79 →	+0.456	+2.179	.008	.034	3	1
UCEC	ACC1 →	+0.518	+2.820	.004	.035	3	1
UCEC	Lck →	+0.217	+2.321	.031	.035	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

S6 by RDH13 expression — STAD

Explore this box plot interactively →