RDH13

Across TCGA cell cohorts, RDH13 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible RDH13-associated genes across cancer lineages are C10orf120, H2AP, and RTL4. Each is linked with RDH13 in more than 1 cancer types. Because this analysis shows association rather than direction, both RDH13-to-partner and partner-to-RDH13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C10orf120 grouped by RDH13-low versus RDH13-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RDH13→partner) and Y-score (partner→RDH13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	C10orf120 →	+0.030	+5.977	<.001	.001	3	1
SOFT_TISSUE	H2AP →	+0.052	+4.930	<.001	.008	3	1
SOFT_TISSUE	RTL4 →	+0.022	+5.369	<.001	.004	3	1
SOFT_TISSUE	MDFIC2 →	+0.228	+4.930	<.001	.008	3	1
LARGE_INTESTINE	CLPSL1 →	+0.158	+4.054	<.001	.004	3	1
LARGE_INTESTINE	PPEF2 →	+0.035	+3.736	.005	.007	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

C10orf120 by RDH13 expression — SOFT_TISSUE

Explore this box plot interactively →