RDH10

Across TCGA cell cohorts, RDH10 mutation is significantly associated with the RNA expression of many other genes, with 23 significant associations in total. PANCREAS shows the largest number of these associations.

The most reproducible RDH10-associated genes across cancer lineages are OR1N1, ATXN3L, and PTCRA. Each is linked with RDH10 in more than 1 cancer types. Because this analysis shows association rather than direction, both RDH10-to-partner and partner-to-RDH10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR1N1 grouped by RDH10-low versus RDH10-high in PANCREAS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RDH10→partner) and Y-score (partner→RDH10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	OR1N1 →	+0.042	+5.000	<.001	.006	3	2
PANCREAS	ATXN3L →	+0.035	+5.000	<.001	.006	3	1
PANCREAS	PTCRA →	+0.023	+5.614	<.001	.002	3	1
PANCREAS	DHRS7C →	+0.065	+5.000	<.001	.006	3	1
PANCREAS	ZIM2 →	+0.035	+5.000	<.001	.006	3	1
BREAST	CSN1S1 →	+0.025	+3.963	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 23 associations by consensus.

OR1N1 by RDH10 expression — PANCREAS

Explore this box plot interactively →