RCVRN

Across TCGA pan-cancer cohorts, RCVRN Mutation is linked to patient survival in 5 of 34 cancer types, making it a survival-associated RCVRN data layer compared with 21 for mass-spec protein and 1 for mass-spec protein.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher RCVRN Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated RCVRN expression acts as an unfavorable survival marker.

HNSC, ACC, and LIHC are the cancer types where RCVRN Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Median	All	0.079	0.768	<.001	48	view →
ACC	OS	Median	All	0.118	0.624	.038	6	view →
LIHC	OS	Median	All	0.025	0.775	<.001	6	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →
SKCM	OS	Median	III,IV	0.179	0.721	<.001	5	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

RCVRN–HNSC (OS)

Open the HNSC breakdown →