RCVRN

Across TCGA patient cohorts, RCVRN RNA expression is significantly associated with the go_rna of many other GO terms, with 7,149 significant associations in total. STAD shows the largest number of these associations.

The most reproducible RCVRN-associated GO terms across cancer lineages are Regulation of cell-substrate adhesion, Positive regulation of myeloid cell differentiation, and Rho protein signal transduction. Each is linked with RCVRN in more than 26 cancer types. Because this analysis shows association rather than direction, both RCVRN-to-partner and partner-to-RCVRN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of cell-substrate adhesion grouped by RCVRN-low versus RCVRN-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RCVRN→partner) and Y-score (partner→RCVRN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of cell-substrate adhesion →	+0.077	+0.192	<.001	<.001	3	27
STAD	Positive regulation of myeloid cell differentiation →	+0.062	+0.193	<.001	<.001	3	25
STAD	Rho protein signal transduction →	+0.065	+0.176	<.001	<.001	3	25
STAD	Regulation of cell shape →	+0.070	+0.174	<.001	<.001	3	25
STAD	Regulation of myeloid cell differentiation →	+0.057	+0.185	<.001	<.001	3	24
SCLC	Positive regulation of cell-substrate adhesion →	+0.111	+0.221	<.001	<.001	2	25

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,149 associations by consensus.

Regulation of cell-substrate adhesion by RCVRN expression — STAD

Explore this box plot interactively →