RCSD1

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RCSD1 mutation is significantly associated with the total protein of many other genes, with 18 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RCSD1-associated genes across cancer lineages are eEF2, JNK_pT183_Y185, and c-Met_pY1235. Each is linked with RCSD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both RCSD1-to-partner and partner-to-RCSD1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RCSD1→partner) and Y-score (partner→RCSD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECeEF2 →+0.420+2.321.019.03532
UCECJNK_pT183_Y185 →-0.210-2.999.013.03532
SKCMc-Met_pY1235 →-0.114-3.169.012.01932
UCEC14-3-3_beta →-0.132-2.973.008.03531
UCECJNK2 →+0.209+2.321.036.03531
UCECMEK1 →+0.476+3.459.009.00531
Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

Exploration