Across TCGA cell cohorts, RCSD1 mutation is significantly associated with the RNA expression of many other genes, with 12 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RCSD1-associated genes across cancer lineages are GALP, EN1, and BPIFB6. Each is linked with RCSD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both RCSD1-to-partner and partner-to-RCSD1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RCSD1→partner) and Y-score (partner→RCSD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	GALP →	+0.022	+5.415	<.001	.004	3	1
LARGE_INTESTINE	EN1 →	+0.831	+3.536	.009	.003	3	1
LARGE_INTESTINE	BPIFB6 →	+0.014	+3.700	<.001	.009	3	1
LARGE_INTESTINE	OR2T33 →	+0.131	+2.845	.001	.009	3	1
LARGE_INTESTINE	OR2T8 →	+0.167	+3.584	<.001	.004	3	1
LARGE_INTESTINE	ANKRD63 →	+0.287	+3.700	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

Exploration

RCSD1 survival (RNA) · tumor vs normal (RNA) · all RCSD1 data types