RCOR3

Across TCGA pan-cancer cohorts, RCOR3 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated RCOR3 data layer compared with 24 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher RCOR3 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated RCOR3 expression acts as an unfavorable survival marker, although some lineages such as PDAC and LUAD show a favorable association.

PDAC, LUAD, and HNSC are the cancer types where RCOR3 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	OS	Quartile	III,IV	0.971	0.364	.004	23	view →
LUAD	OS	Tertile	All	0.974	0.757	.002	14	view →
HNSC	OS	Tertile	All	0.636	0.847	.014	6	view →
LSCC	DFS	Tertile	All	0.809	0.365	.036	4	view →
UCEC	DFS	Median	All	0.922	0.795	.032	2	view →
GBM	OS	Quartile	All	0.552	0.296	.028	2	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

RCOR3–PDAC (OS)

Open the PDAC breakdown →