RCOR3

Across TCGA patient cohorts, RCOR3 mutation is significantly associated with the immune_cell of many other genes, with 7 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RCOR3-associated genes across cancer lineages are MPP, Neutrophils, and CLP. Each is linked with RCOR3 in more than 3 cancer types. Because this analysis shows association rather than direction, both RCOR3-to-partner and partner-to-RCOR3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MPP grouped by RCOR3-low versus RCOR3-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RCOR3→partner) and Y-score (partner→RCOR3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	MPP →	+0.030	+3.403	.005	.035	3	4
LIHC	Neutrophils →	+0.018	+2.579	.014	.036	3	2
STAD	CLP →	+0.082	+2.857	.019	.034	3	1
UCEC	lymphatic Endothelial cells →	-0.022	-3.138	.029	.019	3	1
UCEC	Endothelial cells →	-0.038	-2.072	.020	.019	1	2
UCEC	Class-switched memory B-cells →	-0.064	-3.906	.010	<.001	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

MPP by RCOR3 expression — COAD

Explore this box plot interactively →