RCOR2

Across TCGA pan-cancer cohorts, RCOR2 mass-spec protein is linked to patient survival in 2 of 34 cancer types, making it a survival-associated RCOR2 data layer compared with 24 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher RCOR2 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated RCOR2 expression acts as an unfavorable survival marker, although some lineages such as LSCC show a favorable association.

LSCC and UCEC are the cancer types where RCOR2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	OS	Median	II,III,IV	0.871	0.528	.009	6	view →
UCEC	DFS	Median	All	0.931	1.000	.019	4	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

RCOR2–LSCC (OS)

Open the LSCC breakdown →