RCOR2

Across TCGA patient cohorts, RCOR2 mutation is significantly associated with the total protein of many other genes, with 8 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RCOR2-associated genes across cancer lineages are Notch1, PCNA, and MSH6. Each is linked with RCOR2 in more than 2 cancer types. Because this analysis shows association rather than direction, both RCOR2-to-partner and partner-to-RCOR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Notch1 grouped by RCOR2-low versus RCOR2-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RCOR2→partner) and Y-score (partner→RCOR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	Notch1 →	+0.278	+2.815	.006	.036	2	3
COAD	PCNA →	+0.267	+2.815	.049	.036	3	2
UCEC	MSH6 →	-0.406	-3.169	.010	.018	3	2
COAD	GAPDH →	+0.691	+2.820	.012	.035	3	1
UCEC	N-Cadherin →	+0.299	+2.817	.003	.036	3	1
UCEC	p27 →	+0.212	+3.000	.044	.036	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

Notch1 by RCOR2 expression — COAD

Explore this box plot interactively →