RCOR2

Across TCGA cell cohorts, RCOR2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,497 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible RCOR2-associated GO terms across cancer lineages are Regulation of DNA repair, Negative regulation of transcription by RNA polymerase I, and Positive regulation of double-strand break repair. Each is linked with RCOR2 in more than 12 cancer types. Because this analysis shows association rather than direction, both RCOR2-to-partner and partner-to-RCOR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of DNA repair grouped by RCOR2-low versus RCOR2-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RCOR2→partner) and Y-score (partner→RCOR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Regulation of DNA repair →	+0.050	+1.733	.002	.003	3	13
CNS	Negative regulation of transcription by RNA polymerase I →	+0.102	+1.271	<.001	<.001	3	13
SOFT_TISSUE	Positive regulation of double-strand break repair →	+0.069	+1.604	<.001	<.001	3	12
SOFT_TISSUE	Positive regulation of DNA repair →	+0.051	+1.203	<.001	<.001	3	11
SOFT_TISSUE	Positive regulation of monoatomic ion transport →	-0.118	-2.569	<.001	<.001	3	10
SOFT_TISSUE	Positive regulation of DNA recombination →	+0.075	+2.093	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,497 associations by consensus.

Regulation of DNA repair by RCOR2 expression — LUNG_SCLC

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