RCOR2

Across TCGA cell cohorts, RCOR2 protein abundance is significantly associated with the go_rna of many other GO terms, with 1,975 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RCOR2-associated GO terms across cancer lineages are DNA-templated transcription initiation, Protein-DNA complex organization, and Mitotic DNA integrity checkpoint signaling. Each is linked with RCOR2 in more than 8 cancer types. Because this analysis shows association rather than direction, both RCOR2-to-partner and partner-to-RCOR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA-templated transcription initiation grouped by RCOR2-low versus RCOR2-high in BONE.

protein abundance associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RCOR2→partner) and Y-score (partner→RCOR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	DNA-templated transcription initiation →	+0.122	+0.411	.001	<.001	3	9
LARGE_INTESTINE	Protein-DNA complex organization →	+0.065	+0.462	<.001	<.001	3	7
KIDNEY	Mitotic DNA integrity checkpoint signaling →	+0.060	+0.516	.001	.004	3	7
LARGE_INTESTINE	Negative regulation of cell cycle process →	+0.043	+0.287	<.001	.001	3	7
CNS	Rostrocaudal neural tube patterning →	+0.141	+0.315	.001	.001	3	7
LUNG_SCLC	Epigenetic regulation of gene expression →	+0.048	+0.193	.003	.009	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,975 associations by consensus.

DNA-templated transcription initiation by RCOR2 expression — BONE

Explore this box plot interactively →