RCOR2

Across TCGA cell cohorts, RCOR2 mutation is significantly associated with the RNA expression of many other genes, with 31 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RCOR2-associated genes across cancer lineages are OR8B12, OR8B4, and CRYBB1. Each is linked with RCOR2 in more than 1 cancer types. Because this analysis shows association rather than direction, both RCOR2-to-partner and partner-to-RCOR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR8B12 grouped by RCOR2-low versus RCOR2-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RCOR2→partner) and Y-score (partner→RCOR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	OR8B12 →	+0.023	+5.807	<.001	.001	3	1
OVARY	OR8B4 →	+0.020	+5.807	<.001	.001	3	1
LARGE_INTESTINE	CRYBB1 →	+0.722	+2.878	<.001	.009	3	1
LARGE_INTESTINE	GRM4 →	+1.048	+3.491	<.001	.004	3	1
LARGE_INTESTINE	OR2AT4 →	+0.017	+3.518	<.001	.001	3	1
LARGE_INTESTINE	OR4F21 →	+0.150	+2.878	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 31 associations by consensus.

OR8B12 by RCOR2 expression — OVARY

Explore this box plot interactively →